Endocrine Abstracts

Purpose: To evaluate if patients with low- or intermediate-risk differentiated thyroid cancer (DTC) can be discharged to primary care.Material and Methods: The clinical records and evolution of 346 patients with DTC who had undergone surgery between 1995 and 2020 with a follow-up after a mean of 7.6 ± 6.1 years were retrospectively reviewed. All had a low or intermediate risk of recurrence as defined under the 2015 ATA risk stratification system and...

Background: Patients who require levothyroxine (LT4) supplementation after total thyroidectomy often have difficulty achieving target TSH levels. Several studies have attempted to develop a dosing schedule considering different factors such as age, gender, weight, or body mass index (BMI) as potential determinants of the correct dose of LT4. The objective of this study is to determine if a scheme that uses the percentage of body fat (%BF) measured by CUN-BAE is more accurate t...

Background: The incidence of thyroid cancer (TC) has been increasing in recent years while mortality has remained stable. The cause of this increase is unclear, although several hypotheses have been proposed. While the increased incidence may only be apparent due to increased testing, there is data that suggest that there may be a real increase in incidence related to different risk factors. The aim of this meta-analysis was to determine the current incidence of TC in Europe.<...

Introduction: Immune checkpoint inhibitors (ICIs) are an effective treatment for advanced cancer, but they are not free from immune-related adverse events (irAEs). A common irAES is thyroid dysfunction (TD-irAEs) and, as such, may influence patient survival and response to ICIs.Objetives: The aim was to determine the incidence and characteristics of TD-irAEs among patients with advanced cancer treated with ICIs in a real-life setting and to investigate t...